Benefits of Ionised Hydrogen water

There are hundreds and thousands of articles and testimonials, which show the healing benefits of ionised hydrogen water.Free-Molecular hydrogen is a unique molecular combination of two hydrogen atoms, bonded together, but not to any other elements.Ionised Hydrogenated water is known to protect and heal the kidneys, heart, liver, stomach, intestines, skin, brain, lungs, eyes and pretty much every part of the body.

The best way to consume free-Molecular hydrogen is through ionised water.

The most widely used and possibly the most therapeutic form of free-molecular hydrogen is in ionised water. Ionised water is infused with free molecular hydrogen that is produced by a water ioniser machine, which splits the water in two streams, alkaline and acidic. The alkaline water is packed with free hydrogen and so is therapeutic for that reason as well as the fact of being an alkaline pH.

Molecular hydrogen's ability to scavenge free radicals anywhere in the body

Molecular Hydrogen is known by many prominent researchers world-wide for its ability to truly penetrate through cell membranes (even the blood-brain barrier) and scavenge free radicals.

One reason Hydrogen is not like any other antioxidant is due to its tiny size. Hydrogen is also lipid soluble, which is important, because lipid solubility is necessary for entering into cells through the cell membranes. So, Hydrogen (unlike any other antioxidant) can get into every living part of the body. All other antioxidants are incapable of this feat. Another thing that makes it different from all other free-radical scavengers is that it simply evaporates or turns into water when it's "used up", so it creates no danger of becoming a free-radical itself as other antioxidants do.

Free molecular hydrogen - safest antioxidant available

As we all know, the combination of H2 and Oxygen makes water, which is at the source of all life forms. Oxygen also brings life, but unfortunately complications arise when there is too much oxygen within the body and there is not enough balance of hydrogen. Oxygen can actually become a dangerous free radical within the body when it has lost its electron balance. When it's in this state it's called reactive Oxygen species which causes severe damage to cells,This condition is called Oxidative Stress, and is thought to be at the root of almost all disease.

a tiny little molecular hydrogen can calm it down completely; neutralise it; turn it into harmless water and make it useful for the body. This is done with no harmful waste or byproducts produced.

At the same time molecular hydrogen doesn't attack good radicals in the body. It will never act as a poison to the body, and any excess of it will simply evaporate harmlessly and combine with oxygen in the air to hydrate or moisturise it.

Other types of antioxidants have been found to become free-radicals, themselves, once they have donated their electron to neutralise another molecule. This doesn't happen with molecular hydrogen. As a matter of fact molecular hydrogen is able to refresh the antioxidant abilities of various other antioxidants to keep them from becoming free-radicals. After much testing and scrutinising by research scientists worldwide, no negative effects whatsoever have been found to be caused by molecular hydrogen.

Fighting free-radicals and heart disease

Dr. Shigeo Ohta (of Japan) specifically devoted many years of research on the free radical benefits of ionised water and hydrogen water. Free-hydrogen (molecular hydrogen) was shown to effectively neutralise free-radicals, without any of the negative side-effects often seen with other antioxidants. This is important. Fighting free-radicals while battling (or preventing) cancer, heart disease or 170 other diseases is a huge benefit that alkaline ionised water and hydrogen water both offer. In this video Dr. Ohta, is being interviewed by the CEO of the Molecular Hydrogen Foundation. They talk about the latest research into Molecular Hydrogen and the benefits of hydrogen water and hydrogen gas.

Here is another video where Tyler LeBaron of the Molecular Hydrogen Foundation explains this research in more detail, using charts and peer reviewed reports to clarify his statements.

Here is a partial list of diseases hydrogen antioxidants (molecular hydrogen) have been shown to help.

Alexander disease Allergies Alzheimer's disease and other dementias Angina Asthma Atherosclerosis Athlete's foot Atopic dermatitis Bed sores Bone Loss Cancer (various types) Cardio renal symptoms Cataracts Cerebral haemorrhage Chemo's negative side effects Crohn's disease Chronic fatigue syndrome Cirrhosis Collagen disease Colon diseases Cystic fibrosis Dehydration Diabetes mellitus Diabetic necrosis Frontotemporal lobar degeneration Glaucoma Gout Heart attacks Heart disease or coronary artery disease, HGC disorders High blood pressure Huntington's disease Hypersensitive disorders Hypertension Inflammatory disorders Ischemic brain injuries Kawasaki's disease Kidney disease Liver disease Lupus Malaise Metabolic syndrome Muscle fatigue of athletes

Hydrogen Research on Cancer

The articles in this section show that hydrogenated ionised water inhibits cancer progression and improves the prognosis of cancer patients.

Alkaline ionised water has been proven to help alkalize the body, which is essential in cancer prevention. It helps us to maintain the proper pH balance within cells and organs and so is protective of our cells and a preventative measure against cancer.

Hydrogen water research has also shown many cancer prevention and healing benefits for patients being treated with cancer as well.

This short, 2-minute video, summarises what researchers have worked years to learn about keeping a healthy, disease-free colon, as well as other organs and cells. Colorectal cancer is one of the most dangerous, common and horrible-to-live-with cancers. Don't wait to be diagnosed with colorectal cancer. It's very common in the US to get this disease, and it can be prevented.

Hydrogen Research on Diabetes

These studies show that hydrogen-water helps improve blood glucose control,

The following video presentation is by Mr. Darnell of the "Diabetes Support Services" organisation. In this video you can get a history of water ioniser research and how using ionised water has helped his group members. The history of water ionisers all started by people noticing there were pockets of "healing waters" around the world, and then scientists tested those waters and developed equipment (water ionisers) to simulate the healing waters. Mr. Darnell learned about these waters and this equipment, water ionisers, in a roundabout way, and then after fully studying the subject and equipment, he made recommendations to his group to use ionised water with the group's diabetic members. He reports that ionised water has been very effective in helping the hundreds of diabetic patients in his organisation live better lives, free of many of the complications associated with diabetes. This next section (after the video) is all about the interesting history of these machines.

Ionized water used for the cure of diabetic necrosis

Because of Diabetic Necrosis this hospital patient was almost about to have his leg cut off. He was cured of this condition using ionised water.

This report shows benefits of both alkaline and acidic ionised water.

Research Articles on the Positive Effects of Ionised Hydrogen Water / Inhalation On the Heart

# 1 Leading cause of Death is cardiovascular event

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
Spanning over 20 years worth of treating patients with ionised water	Blood Pressure	Use of Ionized water in hypochlorhydria or achlorhydria Prof. Kuninaka Hironage, Head of Kuninaka Hospital.. "The consumption of alkaline antioxidant water for a period of 2 to 3 months, I have observed the blood pressure slowly drop, due to the water's solvent ability, which dissolves the cholesterol in the blood vessels ."
2017	Myocardial Infarction	The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodelling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction.. - First Pilot Study in Humans. [Human study shows inhaling hydrogen is safe and improves the markers of hypertension.]
2019	Hypertension	Hydrogen gas improves left ventricular hypertrophy in Dahl rats of salt-sensitive hypertension.. [Animal study shows hydrogen reduces hypertension and left ventricular hypertrophy.]
2018	Chronic Heart Failure	Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats.. [Animal study shows hydrogen reduces the symptoms of chronic heart failure.]
2016	Cardiopulmonary Resuscitation	Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats.. [Animal study shows hydrogen improves cardiac function after cardiac arrest.]
2015	Cardiac Dysfunction	Treatment with hydrogen molecules attenuates cardiac dysfunction in streptozotocin-induced diabetic mice.. [Animal study shows hydrogen improves heart function and reduces heart dysfunction caused by high glucose levels caused by diabetes.]
2015	Atherosclerosis	Molecular hydrogen stabilises atherosclerotic plaque in low-density lipoprotein receptor-knockout mice.. [Animal study shows hydrogen has an inhibitory effect and improves the stability of atherosclerotic plaque]
2012	Cardiac Arrest	H(2) gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model.. [Animal study shows hydrogen reduces the mortality rate and increases the rate of resuscitation rate after cardiac arrest.]
2014	Cardiac Arrest	Hydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management.. [Animal study shows hydrogen improves the outcome and resuscitation rate after cardiac arrest.]
2018	Vascular Ageing of Aorta	Administration of hydrogen-rich water prevents vascular ageing of the aorta in LDL receptor-deficient mice.. [Animal study shows hydrogen decreased the markers of vascular ageing and cholesterol levels]

Research Articles on the Positive Effects of Hydrogenated Ionized Water on Cancer

# 2 Leading cause of death is Cancer

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2019	Colorectal cancer	Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer.. [Human study shows hydrogen reverses imbalances caused by chemotherapy and improved prognosis of stage IV cancer patients.]
2017	Colorectal Cancer [LIVER]	Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.. [A controlled, randomised, single-blind human clinical study shows that hydrogen water alleviates liver injury due to chemotherapy.]
2018	Lung Cancer	Hydrogen gas inhibits lung cancer progression through targeting SMC3.. [Animal study shows hydrogen inhibits lung cancer progression.]
2017	Colon Cancer Inhibition	Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer.. [Animal study shows hydrogen improves the survival rate of mice with colon cancer and has anticancer functions, particularly in combination with 5-fluorouracil.]
2013	Mitochondria's huge Influence on Cancer	Mitochondria and Cancer, Past, Present and Future.. [A summary of the research on mitochondria's influence on cancer.
2009	Alleviates Cancer Drug Side-Effects	Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice [Animal study shows hydrogen helps protect against cisplatin-induced toxicity showing it has potential for improving the quality of life of patients undergoing chemotherapy.]

Research Articles on the Positive Effects of Ionized Hydrogen Water on Chronic Lower Respiratory Disease

# 3 Leading cause of Death is Chronic lower respiratory disease

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2017	anti-inflammatory [RHINITIS]	Effect of hydrogen-rich saline on the CD4(+) CD25(+) Foxp3(+) Treg cells of allergic rhinitis guinea pigs model.. [Animal study shows hydrogen reduces allergic inflammation.]
2017	anti-inflammatory [Lung Injury from O2 THERAPY]	Hydrogen alleviates hyperoxic acute lung injury related endoplasmic reticulum stress in rats through upregulation of SIRT1.. [A controlled, randomised, single-blind human clinical study shows that hydrogen water alleviates liver injury due to chemotherapy.]
2015	anti-inflammatory [EXERCISE]	Hydrogen-rich water inhibits mitochondrial oxidative stress and inflammation in the skeletal muscle after eccentric exercise.. [Animal study shows [Animal study shows hydrogen reduces inflammation after exercise.]
2009	Immune System	The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice. [Animal study shows hydrogen water assists immune responsiveness.]

Research Articles on the Positive Effects of Hydrogen Water and Ionized Water on Stroke Victims

# 4 Leading cause of death is stroke

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2017	Cerebral infarction (acute)	Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomised Controlled Clinical Study on Safety and Neuroprotection.. [A randomised controlled human clinical study of patients with acute cerebral infarctions showed no harmful effects and better recovery rates.]
2017	Neuroblastoma	Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis.. [A human cultured neuroblastoma, pre-treated with hydrogen, was protected against H2O2 induced cell death.]
2019	Glioblastoma	Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation.. [Animal study shows reduction in common brain tumours by inhaling hydrogen.]
2018	Traumatic Brain Injury	Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway.. [Animal study shows hydrogen-rich water has a neuroprotective effect on the brain.]
2018	Mitochondria	Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages.. [Animal study shows the neuroprotective effect of hydrogen on the neurons in the spinal cord. Hydrogen was also seen to help the neurons and their mitochondria to heal after damage.]
2018	After stroke	Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signalling pathway.. [Animal study showing the neuroprotective effect of hydrogen.]
2018	Stroke	Hydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis.. [Animal study showing that hydrogen helps improve recovery after stroke.]
2018	Severe Brain Injury	Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral haemorrhage model.. [Animal study showing that hydrogen has a neuroprotective effect on the brain and helps prevent or reduce the effects of brain injury.]
2016	Brain injury	Effect of hydrogen-rich water on the angiogenesis in lesion boundary brain tissue of traumatic brain.. [Animal study shows hydrogen-rich water promotes angiogenesis and improves nerve function.]
2015	Neuroprotective	Hydrogen has a neuroprotective effect via activation of Nrf-2/HO-1 pathway in ischemia reperfusion rat.. [Animal study shows that hydrogen has a neuroprotective effect against stroke.]
2016	Brain damage	Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats.. [Animal study shows hydrogen reduces the effects of brain damage and prevents inflammation.]
2016	Brain infarction	Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats - A possible new hydrogen resource for clinical use.. [Animal study shows hydrogen has a neuroprotective effect against cerebral damage.]
2015	Stroke	Hydrogen improves neurological function through attenuation of blood–brain barrier disruption in spontaneously hypertensive stroke-prone rats.. [Animal study shows hydrogen water can improve neurological function after a stroke.]
2015	Protects Against Stroke	Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins.. [Animal study shows hydrogen water helps to reduce brain infarct volume and improve neurological function following an induced brain injury.]

Research Articles on the Positive Effects of Ionized Hydrogen Water / inhalation on Alzheimer's , Multiple sclerosis & Parkinson's

# 5 Leading Cause of death is Alzheimer’s Disase

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2013	Parkinson's	Pilot study of H2 therapy in Parkinson's disease: A randomised double‐blind placebo‐controlled trial.. [A human controlled trial shows that drinking Hydrogen water was safe, and well tolerated. The patients who drank it showed significant improvement, while the control group who didn’t drink the hydrogen water worsened.]
2019	Vascular Dementia	FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia.. [Animal study shows drinking hydrogen water inhibits neuron loss and alleviates memory impairments due to vascular dementia.]
2019	Glioblastoma	Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation.n.. [Animal study shows reduction in common brain tumours by inhaling hydrogen.]
2018	Mitochondria	Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages.. [Animal study shows the neuroprotective effect of hydrogen on the neurons in the spinal cord. Hydrogen was also seen to help the neurons and their mitochondria to heal after damage.]
2018	Mild Cognitive Impairment	Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomised Clinical Study on Mild Cognitive Impairment. [Animal study showing that hydrogen water helps to suppress dementia and other oxidative stress.]
2018	Cognitive Impairment	Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance.. [Animal study showing that hydrogen significantly helps cognitive behaviour and reduces oxidative stress and inflammation in the brain. This study noted that there was an even more profound effect in the female brains than male.]
2015	Multiple Sclerosis	Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice.. [Animal study shows hydrogen water helps to both delay the onset of and reduce the severity of induced multiple sclerosis.]
2015	Altzheimer's	Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells.. [Animal study shows hydrogen water reduces reactive oxygen induced cell death and stimulates healing.]
2014	Age related Neurological Diseases	Electrochemically Reduced Water Protects Neural Cells from Oxidative Damage.. [Animal study shows hydrogen water protects cells from oxidative stresses.]

Research Articles on the Positive Effects of ionized Hydrogen Water on Diabetes

# 6 Leading Cause of death is Diabetes

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2008	Diabetes [GLUCOSE TOLERANCE]	Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance.. [A randomised double-blind human study shows hydrogen helped decrease oxidative stress and insulin resistance and improved glucose metabolism.]
2013	Diabetes [GLUCOSE UPTAKE]	Hydrogen Improves Glycemic Control in Type1 Diabetic Animal Model by Promoting Glucose Uptake into Skeletal Muscle.. [Animal study shows hydrogen improves glucose control.]
2011	Diabetes [Pt NANOPARTICLES]	Anti-diabetes effect of water containing hydrogen molecule and Pt nanoparticles.. [Animal study shows both hydrogen water and the nano platinum in ionised water improve glucose signalling pathways.]
2006	Diabetes [ANTI-DIABETIC EFFECTS]	Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice.. [Animal study shows hydrogen improves blood glucose control.]
2006	Diabetes [BETA CELL PROTECTION]	Preservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice.. [Animal study shows hydrogen improves blood glucose tolerance, increases blood insulin and reduces blood glucose.]
2005	Diabetes [BETA CELL PROTECTION]	Protective mechanism of reduced water against alloxan-induced pancreatic beta-cell damage: Scavenging effect against reactive oxygen species.. [Animal study shows hydrogen enhances glucose-sensitivity, glucose response of beta-cells and protects pancreatic beta-cells from alloxan-induced cell damage.]

Research Articles on the Positive Effects of Hydrogen Water and Ionized Water on the Kidneys

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2018	Dialysis	Novel hemodialysis (HD) treatment employing molecular hydrogen (H2)-enriched dialysis solution improves prognosis of chronic dialysis patients: A prospective observational study.. [This is a human study spanning 3 years and shows that adding hydrogen to the dialysis solution benefits dialysis patients’ prognosis.]
2003	Kidney Disease	Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water.. [This is a human study which shows that ionised water is effective in reducing oxidative stress and improving overall health of patients with kidney disease. This is important, because hemodialysis increases oxidative stress and to be able to combat that would naturally improve the patient prognosis.]
2018	Toxicity	Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice.. [Animal study shows ionised water helps to protect the kidneys against damage when “Cisplatin” (a chemotherapy drug) is given]
2017	Renal Injury & Fibrosis	Hydrogen Rich Water Attenuates Renal Injury and Fibrosis by Regulation Transforming Growth Factor.. [Animal study shows hydrogen water helps to inhibit the development of fibrosis in kidneys.]
2010	Renal Injury	Intake of water with high levels of dissolved hydrogen (H2) suppresses ischemia-induced cardio-renal injury in Dahl salt-sensitive rats.. [Animal study shows hydrogen water helped healing after a kidney injury.]
2014	Renal injury	Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats.. [Animal study shows hydrogen water helps to alleviate renal injury .]

Research Articles on the Positive Effects of Ionized Hydrogen Water on the Liver

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2017	Chemo: Protects Liver	Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.. [This is a human study which shows that H2 helps to maintain microcirculation and the health of the mitochondria in patients being treated with chemotherapy.]
2011	Radiotherapy for liver tumours	Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumours.. [This is a human study which shows that drinking hydrogen-rich water reduces the stress markers connected with radiation therapy.]
2013	Chronic Hepatitis B	Effect of Hydrogen‐Rich Water on Oxidative Stress, Liver Function, and Viral Load in Patients with Chronic Hepatitis B.. [This is a human study showing that hydrogen rich water helps to alleviate oxidative stress in patients with chronic Hepatitis B.]
2018	Liver Injury	Post-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study.. [Animal study shows H2 to be effective in maintaining microcirculation and mitochondrial function in liver cells and suppressing cellular death in the liver after cardiac death.]
2018	Renal Injury	Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice.. [Animal study shows alkaline ionised water assists the intestinal environment and has beneficial roles for health in terms of cholesterol metabolism and liver protection.]
2017	Liver Injury	Inhalation of high concentrations of hydrogen ameliorates liver ischemia/reperfusion injury through A2A receptor mediated PI3K-Akt pathway.. [Animal study shows that a high concentration of hydrogen improves liver function and may protect the liver against I/R injury, which is the injury when blood supply returns to tissue after a period of absence.]
2017	Protect Against SepsisLiver Injury	Pre-administration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury.. [Animal study shows drinking hydrogen water prolongs life and reduces cell death and oxidative stress in mice with sepsis (a life-threatening response to infection).]
2009	Liver	Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice.. [Animal study shows ionised water protects against liver damage.]

Research Articles on the Positive Effects of Ionized Hydrogen Water on Cholesterol Research Articles on the Positive Effects of Ionized Hydrogen Water on the Intestines & Stomach Research Articles on the Positive Effects of Hydrogen Water and Ionized Water on the Skin Research Articles on the Positive Effects of Hydrogen Water on Inflammation Research Articles on the Positive Effects of Hydrogen Water on Free-Radicals Research Articles Related to the Positive Effects of Ionized Hydrogen Water on Aging Research articles on Ionized hydrogen water on eyes Research articles on many other pathologies Ionized Hydrogen water in pregnancy Ionized Water Used for Cure of Atopic Dermatitis: Hospital Rept Ionized Water Used for The Cure of athlete's Foot, Bed Sores & More Mice Experiments With Ionised Water Chicken Experiments With Ionized Water

Research Articles on the Positive Effects of Ionized Hydrogen Water on Cholesterol

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2013	Cholesterol level Balancing	Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome.. [This is a human study which shows drinking ionised water helps cholesterol levels.]
2018	Liver & Cholesterol	Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice.. [Animal study shows drinking ionised water helps intestinal fermentation.]

Research Articles on the Positive Effects of Ionized Hydrogen Water on the Intestines & Stomach

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2019	Gut Flora	Effects of the long-term consumption of hydrogen-rich water on the antioxidant activity and the gut flora in female juvenile soccer players from Suzhou, China.. [This is a human study which shows hydrogen-rich water was healthy for gut flora]
2019	Gastrointestinal Symptoms	Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms.. [This is a human study which shows alkaline ionised water is effective in relieving abdominal complaints. Subjects drinking ionised water also had better rest at night and woke in the morning with more energy.]
2018	Irritable Bowel Syndrome with Diarrhoea	Effects of Alkaline-Reduced Drinking Water on Irritable Bowel Syndrome with Diarrhoea: A Randomised Double-Blind, Placebo-Controlled Pilot Study.. [This is a human study which shows alkaline ionised water was helpful in improving the symptoms of diarrhoea and irritable bowel syndrome.]
2005	Intestinal Health	Selective stimulation of the growth of anaerobic microflora in the human intestinal tract by electrolyzed reduced water.. [This is a human study which shows that alkaline ionised water assists to properly balance the gut microflora.]
2018	Protects-Good Bacteria	Intestinal Microbiota Ecological Response to Oral Administrations of Hydrogen-Rich Water and Lactulose in Female Piglets Fed a Fusarium Toxin-Contaminated Diet.. [Animal study shows that hydrogen-water has shown a protective effect on the balance of intestinal microbiota.]
2018	Intestinal Environment	Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice.. [Animal study shows alkaline ionised water has benefit to intestinal microbes]
2018	GI Toxicity	Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota.. [Animal study shows that drinking hydrogen-rich water improved the prognosis of mice undergoing radiation and was protective of the intestines.]
2017	Inflammatory Bowel Disease	Hydrogen-rich water protects against inﬂammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression.. [Animal study shows hydrogen-rich water protects against inflammatory bowel disease.]
1996	Intestinal Health	Physiological effects of alkaline ionised water: Effects on metabolites produced by intestinal fermentation.. [Animal study shows alkaline ionised water was healthy for the intestines.]

Research Articles on the Positive Effects of Hydrogen Water and Ionized Water on the Skin

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2018	Psoriasis	Positive effects of hydrogen-water bathing in patients of psoriasis and parapsoriasis en plaques.. [This is a human study which shows hydrogen water bathing is beneficial to psoriasis.]
2013	Skin Ulcers	Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro.. [This is a human study which shows intake of hydrogen water helps the reconstruction of normal skin cells.]
2012	Skin Diseases	Hydrogen(H2) treatment for acute erythematous skin diseases. A report of 4 patients with safety data and a non-controlled feasibility study with H2 concentration measurement on two volunteers.. [This is a human study which shows hydrogen helped with the prognosis of inflammation of the skin.]
2012	Wrinkles	Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes.. [This is a human study which shows hydrogen water bathing helps to repress UVA-induced wrinkles.
2013	Dermatitis	The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC/Nga Mice.. [Animal study shows hydrogen water has a positive effect on atopic dermatitis.]

Research Articles on the Positive Effects of Hydrogen Water on Inflammation

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2014	Sports-Related Soft Tissue Injuries	Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries.. [Human study of professional athletes shows faster recovery times when injured for those who were given hydrogen supplements daily during the season.]
2017	anti-inflammatory [RHINITIS]	Effect of hydrogen-rich saline on the CD4(+) CD25(+) Foxp3(+) Treg cells of allergic rhinitis guinea pigs model.. [Animal study shows hydrogen reduces allergic inflammation.]
2017	anti-inflammatory [PANCREATITIS]	Hydrogen Treatment Protects Mice Against Chronic Pancreatitis by Restoring Regulatory T Cells Loss.. [Animal study shows hydrogen helped to prevent and reduce pancreatitis.]
2017	anti-inflammatory [Lung Injury from O2 THERAPY]	Hydrogen alleviates hyperoxic acute lung injury related endoplasmic reticulum stress in rats through upregulation of SIRT1.. [Animal study shows that hydrogen has a protective effect against oxygen induced lung injury and reduces edema.]
2016	anti-inflammatory [PANCREATITIS]	Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis.. [Animal study shows hydrogen has a protective effect against oxidative damage and reduces inflammation.]
2016	anti-inflammatory [ARTHRITIS]	Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress.. [Animal study shows hydrogen slows down the progression of rheumatoid arthritis.]
2015	anti-inflammatory [EXERCISE]	Hydrogen-rich water inhibits mitochondrial oxidative stress and inflammation in the skeletal muscle after eccentric exercise.. [Animal study shows [Animal study shows hydrogen reduces inflammation after exercise.]
2001	anti-inflammatory [LIVER]	Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation.. [Animal study shows hydrogen has an anti-inflammatory effect.]
2009	aImmune System	The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice.. [Animal study shows hydrogen water assists immune responsiveness.]

Research Articles on the Positive Effects of Hydrogen Water on Free-Radicals

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2012	Platelets	Hydrogen may inhibit collagen-induced platelet aggregation: an ex vivo and in vivo study.. [This is a human and animal study which shows hydrogen may inhibit collagen-induced platelet aggregation.]
2016	Antioxidant	Effects of Hydrogenated Water on Intracellular Biomarkers for Antioxidants, Glucose Uptake, Insulin Signalling and SIRT 1 and telomerase Activity.. [in vitro study shows that commercial hydrogen water is effective in antioxidant properties.]
2017	Bone-Health	Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis.. [Animal study shows hydrogen prevents steroid-induced osteonecrosis.]
2011	Eyes - Cornea	Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model.. [Animal study shows hydrogen helps prevent blindness caused by alkali burn.]
2017	Obesity	Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet.. [Animal study shows hydrogen-rich water suppressed body weight gain and reduced oxidative stress.]
2011	Obesity & Diabetes	Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice.. [Animal study shows hydrogen stimulated energy metabolism, improving obesity, diabetes and metabolic syndrome.]

Research Articles Related to the Positive Effects of Ionized Hydrogen Water on Aging

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2018	Reduction of Senescence-Associated Cells	Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo.. [Animal study shows hydrogen is a protective anti-aging treatment.]
2017	Anti-Aging & Cell Death	Hydrogen Treatment Protects against Cell Death and Senescence Induced by Oxidative Damage.. [Animal study shows hydrogen protects against ageing and cell death.]
2016	Longevity	Alkaline Water and Longevity.. [3-year survival study shows alkaline ionised water improves strength and longevity of mice.]
2010	Anti-Aging; Bones	Hydrogen gas treatment prolongs replicative lifespan of bone marrow multipotential stromal cells in vitro while preserving differentiation and paracrine potentials.. [In vitro study shows hydrogen prolongs the lifespan of cells.]
2013	Increased Lifespan	Electrolyzed-reduced water increases resistance to oxidative stress, fertility, and lifespan via insulin/IGF-1-like signal in C. elegans.. [Animal study shows hydrogen helps to resist oxidative stress and ageing.]
1997	Protects DNA	Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage.. [Animal study shows hydrogen helps to protect DNA and scavenges harmful radicals.]

Research articles on Ionized hydrogen water on eyes

YEAR	TOPIC/SUBJECT	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2019	Retinal Vein Occlusion	Protective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression.. [Animal study shows hydrogen helps alleviate retinal edema and improve its function.]
2011	Cornea	Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model.. [Animal study shows hydrogen helps prevent blindness from alkali burn.]
2010	Retina	Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury. Oharazawa H1, Igarashi T, Yokota T.. [Animal study shows hydrogen loaded eye drops are highly useful and neuroprotective]

Research articles on many other pathologies

YEAR	TOPIC/SUBJECT	LINK	TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE
2011	Radiotherapy	PubMed	Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumours.. [A randomised placebo controlled human study shows therapeutic benefits for drinking hydrogen-rich water before, during and after radiation treatments]
2011	Weight Loss	HighBeam	The effect of daily consumption of 2 litres of electrolyzed water for 2 months on body composition and several physiological parameters in four obese subjects: a preliminary report.. [This was a human trial to see if alkaline ionised water would influence the ability of four obese patients to lose weight. The average weight loss reported during the two-month trial was 12 pounds. No other variable was introduced. No toxins were in the water, yet increased toxins were in the urine test, which indicates the body was able to detox several of the tested heavy metals.]
2016	Blood Viscosity	BioMed Central	Effect of electrolyzed high-pH alkaline water on blood viscosity in healthy adults.. [Human study shows high pH water drunk after exercise to be more hydrating. The blood viscosity was tested, and shown to be better, in the group who drank alkaline ionised water vs. acceptable standard purified water.]
2018	Pregnancy: Protective Benefits Spread to Newborn	PubMed	Administration of molecular hydrogen during pregnancy improves behavioural abnormalities of offspring in a maternal immune activation model.. [Animal study shows that giving H2 to the mother is protective for the newborn]
2017	Hemorrhagic Shock	PubMed	Hydrogen gas inhalation inhibits progression to the "irreversible" stage of shock after severe haemorrhage in rats.. [Animal study shows treatment with H2 inhalation stabilises the blood pressure until curative treatment can be performed.]
2014	Hearing Loss (noise-induced)	PubMed	Inhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species.. [Animal study shows H2 inhalation is protective against noise induced hearing loss.]
2016	Sepsis	PubMed	Molecular Hydrogen Therapy Ameliorates Organ Damage Induced by Sepsis.. [Animal study shows molecular hydrogen improves chances of survival]
2016	Motor Deficits	Tandfon-line	Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice.. [Animal study shows hydrogen improves prognosis for muscular dystrophy]
2016	Bladder	PubMed	Preventive Effect of Hydrogen Water on the Development of Detrusor Overactivity in a Rat Model of Bladder Outlet Obstruction.. [Animal study shows H2 is protective against bladder dysfunction.]
2009	Hearing: Auditory Hair Cells	PubMed	Hydrogen protects auditory hair cells from free radicals.. [In vitro study shows hydrogen to be protective against cell death of auditory hair cells.]
2014	Prevention Medicine	PubMed	Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine..
2009	Metabolic Acidosis	PubMed	Ionised alkaline water: new strategy for management of metabolic acidosis in experimental animals.. [Animal study shows alkaline ionised water can manage metabolic acidosis safely.]
2009	Hangovers	PubMed	Electrolyzed-reduced water inhibits acute ethanol-induced hangovers in Sprague-Dawley rats.. [Animal study shows drinking alkaline ionised water has a detox effect from ethanol]
2017	ERW Superior to other H2Water	PubMed	Electrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water.. [In vitro study shows that alkaline ionised water has an additional antioxidative factor, likely to be platinum nanoparticles, which makes it superior to other hydrogen applications for scavenging radicals.]

Ionized Hydrogen water in pregnancy

Use of Ionized water for gynaecological conditions Prof. Watanabe Ifao, Watanabe Hospital experience in his 30 years of clinical practice that "Ionised alkaline antioxidant water improves body constituents and ensures effective healing to many illnesses. The uses of antioxidant water in gynaecological patients have proved to be very effective. The main reason for its effectiveness is that this water can neutralise toxins.

When given antioxidant water to pre-eclamptic toxaemia cases, the results are most significant. During my long years of servicing the pre-eclamptic toxaemia cases, I found that the women with pre-eclamptic toxaemia who consumed antioxidant water tend to deliver healthier babies with stronger muscles. A survey report carried out on babies in this group showed intelligence above average."

Ionized Water Used for Cure of Atopic Dermatitis: Hospital Rept

In another Japanese study, an Atopic Dermatitis patient became cured using ionised water. Atopic dermatitis is an illness accompanied by intense itching. Its cause is unknown. It has been found that this almost-incurable-illness can be cured using ionised water.

This report is from Akashi Hospital in Tokyo, Japan. It shows how Dr. Shinkai has cured thousands of patients with atopic dermatitis using both alkaline and acidic ionised water.

Ionized Water Used for The Cure of athlete's Foot, Bed Sores & More

This report shows several more serious medical problems being cured with alkaline and acidic ionised water.

Mice Experiments With Ionised Water

These experiments with mice show the positive effects found by water ioniser research in Japan and Korea. The video shows impressive results using ionised water with diabetes, cancer, high blood pressure and obesity in mice and rats. The tests, shown in this video, were done in laboratory-controlled conditions and show without a doubt that alkaline ionised water has made significant improvements in multiple health-related conditions, i.e. diabetes, cholesterol, cancer, and more.

Chicken Experiments With Ionized Water

These experiments with chickens are pretty impressive too. The tests, shown in this video, were done in controlled, scientific conditions and show without a doubt that alkaline ionised water has made significant improvements in the overall health and immune systems of chickens.

Medical research