Medical Research

Use of Ionized water in hypochlorhydria or achlorhydria Prof. Kuninaka Hironage, Head of Kuninaka Hospital..

The consumption of alkaline antioxidant water for a period of 2 to 3 months, I have observed the blood pressure slowly drop, due to the water's solvent ability, which dissolves the cholesterol in the blood vessels .

The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodelling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction..

- First Pilot Study in Humans. [Human study shows inhaling hydrogen is safe and improves the markers of hypertension.]

Hydrogen gas improves left ventricular hypertrophy in Dahl rats of salt-sensitive hypertension..

[Animal study shows hydrogen reduces hypertension and left ventricular hypertrophy.]

Use of Ionized water in hypochlorhydria or achlorhydria Prof. Kuninaka Hironage, Head of Kuninaka Hospital..

The consumption of alkaline antioxidant water for a period of 2 to 3 months, I have observed the blood pressure slowly drop, due to the water's solvent ability, which dissolves the cholesterol in the blood vessels .

The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodelling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction..

- First Pilot Study in Humans. [Human study shows inhaling hydrogen is safe and improves the markers of hypertension.]

Hydrogen gas improves left ventricular hypertrophy in Dahl rats of salt-sensitive hypertension..

[Animal study shows hydrogen reduces hypertension and left ventricular hypertrophy.]

Effect of hydrogen-rich saline on the CD4(+) CD25(+) Foxp3(+) Treg cells of allergic rhinitis guinea pigs model..

[Animal study shows hydrogen reduces allergic inflammation.]

Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis..

[A human cultured neuroblastoma, pre-treated with hydrogen, was protected against H2O2 induced cell death.]

Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation..

[Animal study shows reduction in common brain tumours by inhaling hydrogen.]

Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway..

[Animal study shows hydrogen-rich water has a neuroprotective effect on the brain.]

Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages..

[Animal study shows the neuroprotective effect of hydrogen on the neurons in the spinal cord. Hydrogen was also seen to help the neurons and their mitochondria to heal after damage.]

Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signalling pathway..

[Animal study showing the neuroprotective effect of hydrogen.]

Hydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis..

[Animal study showing that hydrogen helps improve recovery after stroke.]

Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral haemorrhage model..

[Animal study showing that hydrogen has a neuroprotective effect on the brain and helps prevent or reduce the effects of brain injury.]

Effect of hydrogen-rich water on the angiogenesis in lesion boundary brain tissue of traumatic brain..

[Animal study shows hydrogen-rich water promotes angiogenesis and improves nerve function.]

Hydrogen has a neuroprotective effect via activation of Nrf-2/HO-1 pathway in ischemia reperfusion rat..

[Animal study shows that hydrogen has a neuroprotective effect against stroke.]

Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats..

[Animal study shows hydrogen reduces the effects of brain damage and prevents inflammation.]

Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats - A possible new hydrogen resource for clinical use..

[Animal study shows hydrogen has a neuroprotective effect against cerebral damage.]

Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats..

[Animal study shows hydrogen water can improve neurological function after a stroke.]

Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins..

[Animal study shows hydrogen water helps to reduce brain infarct volume and improve neurological function following an induced brain injury.]

Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomised Controlled Clinical Study on Safety and Neuroprotection..

[A randomised controlled human clinical study of patients with acute cerebral infarctions showed no harmful effects and better recovery rates.]

Hydrogen alleviates hyperoxic acute lung injury related endoplasmic reticulum stress in rats through upregulation of SIRT1..

[A controlled, randomised, single-blind human clinical study shows that hydrogen water alleviates liver injury due to chemotherapy.]

Hydrogen-rich water inhibits mitochondrial oxidative stress and inflammation in the skeletal muscle after eccentric exercise..

[Animal study shows [Animal study shows hydrogen reduces inflammation after exercise.]

The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice..

[Animal study shows hydrogen water assists immune responsiveness.]

Pilot study of H2 therapy in Parkinson's disease: A randomised double‐blind placebo‐controlled trial..

[A human controlled trial shows that drinking Hydrogen water was safe, and well tolerated. The patients who drank it showed significant improvement, while the control group who didn't drink the hydrogen water worsened.]

FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia..

[Animal study shows drinking hydrogen water inhibits neuron loss and alleviates memory impairments due to vascular dementia.]

Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation.n..

[Animal study shows reduction in common brain tumors by inhaling hydrogen.]

Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages..

[Animal study shows the neuroprotective effect of hydrogen on the neurons in the spinal cord. Hydrogen was also seen to help the neurons and their mitochondria to heal after damage.]

Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomised Clinical Study on Mild Cognitive Impairment.

[Animal study showing that hydrogen water helps to suppress dementia and other oxidative stress.]

Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance..

[Animal study showing that hydrogen significantly helps cognitive behavior and reduces oxidative stress and inflammation in the brain. This study noted that there was an even more profound effect in the female brains than male.]

Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice..

[Animal study shows hydrogen water helps to both delay the onset of and reduce the severity of induced multiple sclerosis.]

Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells..

[Animal study shows hydrogen water reduces reactive oxygen-induced cell death and stimulates healing.]

Electrochemically Reduced Water Protects Neural Cells from Oxidative Damage..

[Animal study shows hydrogen water protects cells from oxidative stresses.]

Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance..

[A randomized double-blind human study shows hydrogen helped decrease oxidative stress and insulin resistance and improved glucose metabolism.]

Hydrogen Improves Glycemic Control in Type1 Diabetic Animal Model by Promoting Glucose Uptake into Skeletal Muscle..

[Animal study shows hydrogen improves glucose control.]

Anti-diabetes effect of water containing hydrogen molecule and Pt nanoparticles..

[Animal study shows both hydrogen water and the nano platinum in ionized water improve glucose signaling pathways.]

Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice..

[Animal study shows hydrogen improves blood glucose control.]

Preservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice..

[Animal study shows hydrogen improves blood glucose tolerance, increases blood insulin and reduces blood glucose.]

Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance..

[Animal study showing that hydrogen significantly helps cognitive behavior and reduces oxidative stress and inflammation in the brain. This study noted that there was an even more profound effect in the female brains than male.]

Protective mechanism of reduced water against alloxan-induced pancreatic beta-cell damage: Scavenging effect against reactive oxygen species..

[Animal study shows hydrogen enhances glucose-sensitivity, glucose response of beta-cells and protects pancreatic beta-cells from alloxan-induced cell damage.]

Novel hemodialysis (HD) treatment employing molecular hydrogen (H2)-enriched dialysis solution improves prognosis of chronic dialysis patients: A prospective observational study.

This is a human study spanning 3 years and shows that adding hydrogen to the dialysis solution benefits dialysis patients' prognosis.

Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water.

This is a human study which shows that ionized water is effective in reducing oxidative stress and improving overall health of patients with kidney disease. This is important because hemodialysis increases oxidative stress and being able to combat that would naturally improve the patient prognosis.

Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice.

Animal study shows ionized water helps to protect the kidneys against damage when 'Cisplatin' (a chemotherapy drug) is given.

Hydrogen Rich Water Attenuates Renal Injury and Fibrosis by Regulation Transforming Growth Factor.

Animal study shows hydrogen water helps to inhibit the development of fibrosis in kidneys.

Intake of water with high levels of dissolved hydrogen (H2) suppresses ischemia-induced cardio-renal injury in Dahl salt-sensitive rats.

Animal study shows hydrogen water helped healing after a kidney injury.

Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats.

Animal study shows hydrogen water helps to alleviate renal injury.

Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.

This is a human study which shows that H2 helps to maintain microcirculation and the health of the mitochondria in patients being treated with chemotherapy.

Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumours.

This is a human study which shows that drinking hydrogen-rich water reduces the stress markers connected with radiation therapy.

Effect of Hydrogen‐Rich Water on Oxidative Stress, Liver Function, and Viral Load in Patients with Chronic Hepatitis B.

This is a human study showing that hydrogen-rich water helps to alleviate oxidative stress in patients with chronic Hepatitis B.

Post-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study.

Animal study shows H2 to be effective in maintaining microcirculation and mitochondrial function in liver cells and suppressing cellular death in the liver after cardiac death.

Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice.

Animal study shows alkaline ionized water assists the intestinal environment and has beneficial roles for health in terms of cholesterol metabolism and liver protection.

Inhalation of high concentrations of hydrogen ameliorates liver ischemia/reperfusion injury through A2A receptor mediated PI3K-Akt pathway.

Animal study shows that a high concentration of hydrogen improves liver function and may protect the liver against I/R injury, which is the injury when blood supply returns to tissue after a period of absence.

Pre-administration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury.

Animal study shows drinking hydrogen water prolongs life and reduces cell death and oxidative stress in mice with sepsis (a life-threatening response to infection).

Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice.

Animal study shows ionized water protects against liver damage.

Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome.

This is a human study which shows drinking ionised water helps cholesterol levels.

Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice.

Animal study shows drinking ionised water helps intestinal fermentation.

Effects of the long-term consumption of hydrogen-rich water on the antioxidant activity and the gut flora in female juvenile soccer players from Suzhou, China.

This is a human study which shows hydrogen-rich water was healthy for gut flora.

Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms.

This is a human study which shows alkaline ionised water is effective in relieving abdominal complaints. Subjects drinking ionised water also had better rest at night and woke in the morning with more energy.

Effects of Alkaline-Reduced Drinking Water on Irritable Bowel Syndrome with Diarrhoea: A Randomised Double-Blind, Placebo-Controlled Pilot Study.

This is a human study which shows alkaline ionised water was helpful in improving the symptoms of diarrhoea and irritable bowel syndrome.

Selective stimulation of the growth of anaerobic microflora in the human intestinal tract by electrolyzed reduced water.

This is a human study which shows that alkaline ionised water assists to properly balance the gut microflora.

Intestinal Microbiota Ecological Response to Oral Administrations of Hydrogen-Rich Water and Lactulose in Female Piglets Fed a Fusarium Toxin-Contaminated Diet.

Animal study shows that hydrogen-water has shown a protective effect on the balance of intestinal microbiota.

Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice.

Animal study shows alkaline ionised water has benefit to intestinal microbes.

Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88's effects on the gut microbiota.

Animal study shows that drinking hydrogen-rich water improved the prognosis of mice undergoing radiation and was protective of the intestines.

Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression.

Animal study shows hydrogen-rich water protects against inflammatory bowel disease.

Physiological effects of alkaline ionised water: Effects on metabolites produced by intestinal fermentation.

Animal study shows alkaline ionised water was healthy for the intestines.

Positive effects of hydrogen-water bathing in patients of psoriasis and parapsoriasis en plaques.

This is a human study which shows hydrogen water bathing is beneficial to psoriasis.

Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro.

This is a human study which shows intake of hydrogen water helps the reconstruction of normal skin cells.

Hydrogen(H2) treatment for acute erythematous skin diseases. A report of 4 patients with safety data and a non-controlled feasibility study with H2 concentration measurement on two volunteers.

This is a human study which shows hydrogen helped with the prognosis of inflammation of the skin.

Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes.

This is a human study which shows hydrogen water bathing helps to repress UVA-induced wrinkles.

The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC/Nga Mice.

Animal study shows hydrogen water has a positive effect on atopic dermatitis.

Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries.

Human study of professional athletes shows faster recovery times when injured for those who were given hydrogen supplements daily during the season.

Effect of hydrogen-rich saline on the CD4(+) CD25(+) Foxp3(+) Treg cells of allergic rhinitis guinea pigs model.

Animal study shows hydrogen reduces allergic inflammation.

Hydrogen alleviates hyperoxic acute lung injury related endoplasmic reticulum stress in rats through upregulation of SIRT1.

Animal study shows that hydrogen has a protective effect against oxygen-induced lung injury and reduces edema.

Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis.

Animal study shows hydrogen has a protective effect against oxidative damage and reduces inflammation.

Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress.

Animal study shows hydrogen slows down the progression of rheumatoid arthritis.

Hydrogen-rich water inhibits mitochondrial oxidative stress and inflammation in the skeletal muscle after eccentric exercise.

Animal study shows hydrogen reduces inflammation after exercise.

Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation.

Animal study shows hydrogen has an anti-inflammatory effect.

Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression.

Animal study shows hydrogen-rich water protects against inflammatory bowel disease.

The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice.

Animal study shows hydrogen water assists immune responsiveness.

Hydrogen may inhibit collagen-induced platelet aggregation: an ex vivo and in vivo study.

This is a human and animal study which shows hydrogen may inhibit collagen-induced platelet aggregation.

Effects of Hydrogenated Water on Intracellular Biomarkers for Antioxidants, Glucose Uptake, Insulin Signalling and SIRT 1 and telomerase Activity.

In vitro study shows that commercial hydrogen water is effective in antioxidant properties.

Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis.

Animal study shows hydrogen prevents steroid-induced osteonecrosis.

Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model.

Animal study shows hydrogen helps prevent blindness caused by alkali burn.

Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet.

Animal study shows hydrogen-rich water suppressed body weight gain and reduced oxidative stress.

Hydrogen-rich water inhibits mitochondrial oxidative stress and inflammation in the skeletal muscle after eccentric exercise.

Animal study shows hydrogen reduces inflammation after exercise.

Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice.

Animal study shows hydrogen stimulated energy metabolism, improving obesity, diabetes, and metabolic syndrome.

Hydrogen may inhibit collagen-induced platelet aggregation: an ex vivo and in vivo study.

This is a human and animal study which shows hydrogen may inhibit collagen-induced platelet aggregation.

Effects of Hydrogenated Water on Intracellular Biomarkers for Antioxidants, Glucose Uptake, Insulin Signalling and SIRT 1 and telomerase Activity.

In vitro study shows that commercial hydrogen water is effective in antioxidant properties.

Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis.

Animal study shows hydrogen prevents steroid-induced osteonecrosis.

Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model.

Animal study shows hydrogen helps prevent blindness caused by alkali burn.

Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet.

Animal study shows hydrogen-rich water suppressed body weight gain and reduced oxidative stress.

Hydrogen-rich water inhibits mitochondrial oxidative stress and inflammation in the skeletal muscle after eccentric exercise.

Animal study shows hydrogen reduces inflammation after exercise.

Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice.

Animal study shows hydrogen stimulated energy metabolism, improving obesity, diabetes, and metabolic syndrome.

Protective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression.

Animal study shows hydrogen helps alleviate retinal edema and improve its function.

Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model.

Animal study shows hydrogen helps prevent blindness from alkali burn.

Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury. Oharazawa H1, Igarashi T, Yokota T..

Animal study shows hydrogen-loaded eye drops are highly useful and neuroprotective.

Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors.

A randomized placebo-controlled human study shows therapeutic benefits for drinking hydrogen-rich water before, during, and after radiation treatments.

The effect of daily consumption of 2 liters of electrolyzed water for 2 months on body composition and several physiological parameters in four obese subjects: a preliminary report.

The effect of daily consumption of 2 liters of electrolyzed water for 2 months on body composition and several physiological parameters in four obese subjects: a preliminary report.

Effect of electrolyzed high-pH alkaline water on blood viscosity in healthy adults.

Human study shows high-pH water drunk after exercise to be more hydrating. The blood viscosity was tested and shown to be better in the group who drank alkaline ionized water vs. acceptable standard purified water.

Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model.

Animal study shows that giving H2 to the mother is protective for the newborn.

Hydrogen gas inhalation inhibits progression to the 'irreversible' stage of shock after severe hemorrhage in rats.

Animal study shows treatment with H2 inhalation stabilizes the blood pressure until curative treatment can be performed.

Inhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species.

Animal study shows H2 inhalation is protective against noise-induced hearing loss.

Molecular Hydrogen Therapy Ameliorates Organ Damage Induced by Sepsis.

Animal study shows molecular hydrogen improves chances of survival.

Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice.

Animal study shows hydrogen improves prognosis for muscular dystrophy.

Preventive Effect of Hydrogen Water on the Development of Detrusor Overactivity in a Rat Model of Bladder Outlet Obstruction.

Animal study shows H2 is protective against bladder dysfunction.

Hydrogen protects auditory hair cells from free radicals.

In vitro study shows hydrogen to be protective against cell death of auditory hair cells.

Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine.

Ionized alkaline water: new strategy for management of metabolic acidosis in experimental animals.

Animal study shows alkaline ionized water can manage metabolic acidosis safely.

Electrolyzed-reduced water inhibits acute ethanol-induced hangovers in Sprague-Dawley rats.

Animal study shows drinking alkaline ionized water has a detox effect from ethanol.

Electrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water.

In vitro study shows that alkaline ionized water has an additional antioxidative factor, likely to be platinum nanoparticles, which makes it superior to other hydrogen applications for scavenging radicals.

Hydrogen may inhibit collagen-induced platelet aggregation: an ex vivo and in vivo study.

This is a human and animal study which shows hydrogen may inhibit collagen-induced platelet aggregation.

Effects of Hydrogenated Water on Intracellular Biomarkers for Antioxidants, Glucose Uptake, Insulin Signalling and SIRT 1 and telomerase Activity.

In vitro study shows that commercial hydrogen water is effective in antioxidant properties.

Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis.

Animal study shows hydrogen prevents steroid-induced osteonecrosis.

Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model.

Animal study shows hydrogen helps prevent blindness caused by alkali burn.

Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet.

Animal study shows hydrogen-rich water suppressed body weight gain and reduced oxidative stress.

Hydrogen-rich water inhibits mitochondrial oxidative stress and inflammation in the skeletal muscle after eccentric exercise.

Animal study shows hydrogen reduces inflammation after exercise.

Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice.

Animal study shows hydrogen stimulated energy metabolism, improving obesity, diabetes, and metabolic syndrome.